I'm currently testing Windows 10 natively on my MacBook Pro (via Bootcamp). I'm using many applications, that are already cross-platform, like Evernote, 1Password, Microsoft Office and Dropbox. For other apps, like TextExpander, I need a special Windows app to have a similar functionality and access to the same set of data. In the case of TextExpander, I'm using Breevy to access and use my TextExpander snippet database.
Even on Windows 10 living a high-dpi desktop lifestyle is sometimes painful. Especially when you are going to access remote desktops: The built-in remote desktop application of Windows 10 doesn't scale remote desktops, and VMware's Horizon View client is failing to scale too. The result is that all fonts are incredibly small and often unreadable. But I found a workaround for VMware's Horizon View. There is a hidden registry key you can use to enable scaling on high-dpi desktops. I'm using TeamViewer to access remote desktops too, and Teamviewer is handling scaling fine.
Next I will try VMware Workstation and check, how scaling for a high-dpi desktop is handled there.